Banca de DEFESA: ROBERTA CRISTINA GOMES DE MEDEIROS DA COSTA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : ROBERTA CRISTINA GOMES DE MEDEIROS DA COSTA
DATA : 30/09/2020
HORA: 09:00
LOCAL: Programa de Pos Graduação em Biologia Experimental
TÍTULO:

EVALUATION OF THE EFFECT OF THE INFECTION BY PLASMODIUM BERGHEI AND TREATMENT WITH COARTEM® ON MUSCULAR NOCICEPTION

PALAVRAS-CHAVES:

Key words: Experimental malaria; Antimalarials; Muscle pain

PÁGINAS: 90
GRANDE ÁREA: Ciências Biológicas
ÁREA: Bioquímica
RESUMO:

BSTRACT A better understanding of the biological processes underlying the progression of disease infection is urgently needed to reduce the morbidity and mortality of malaria. Like many diseases caused by protozoan parasites. Several evidences support the harmful effect of malaria on skeletal and cardiac muscle in animals and humans. Malaria has been shown to cause harmful effects in humans, leading to muscle weakness, muscle fatigue, breathing difficulties, kidney and liver failure, and can lead to cardiac myopathies. Most antimalarial drugs used are active against various stages of the blood parasite. Anti-malarial drugs, widely used, have a short clinical life due to the development of parasite resistance to the drug. In addition to the issue of resistance, another concern is that antimalarials are also associated with the development of adverse reactions, of which the ability to affect skeletal and cardiac muscle stands out. Therefore, the present study intends to experimentally evaluate the effect of treatment with antimalarials on the behavioral responses in a model of muscle pain in male Balb / c mice infected with Plasmodium berghei of the ANKA strain.

MEMBROS DA BANCA:
Interno - 2148421 - CHRISTIAN COLLINS KUEHN
Externo à Instituição - NIDIANE DANTAS REIS PRADO - São Lucas
Presidente - 889.191.881-49 - QUINTINO MOURA DIAS JÚNIOR - UNIR