Banca de DEFESA: MAYRA MENEGUELLI

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : MAYRA MENEGUELLI
DATA : 17/12/2021
HORA: 17:00
LOCAL: Google neet
TÍTULO:

Evaluation of Toxicological Antibacterial and Camu-Camu Pulpsca (Myrciaria dubia)

PALAVRAS-CHAVES:

Amazon Biodiversity; Herbal; Histopathology; Injury repair.

PÁGINAS: 51
GRANDE ÁREA: Outra
ÁREA: Ciências Ambientais
RESUMO:

Wound healing consists of a complex series of cellular and molecular events that interact
to effect tissue repaving and reconstitution. There are numerous technologies that help the
healing process and, among them, the phytochemicals present in medicinal plant species are an
alternative resource that, on several occasions, stand out for their efficiency. In the Amazon, it
can be seen that the population uses several forest products with a medicinal nature. This fact
can be justified by the transfer of empirical ethnobotanical knowledge of man, throughout
history, associated with the harmonious coexistence with nature. Therefore, the vegetable
species Myrciaria dubia (McVaugh) is included, commonly known as camu-camu, which has
antioxidant properties, attributed to its high content of ascorbic acid, present in the fruit's pulp.
However, it is reported that most of this knowledge has not yet been analyzed from a scientific
perspective. Based on the above, the objective of this work was to determine the toxicity,
antibacterial and healing action of the methanol extract of M. dubia pulp and leaf. Thus, this
dissertation was divided into an introduction and two chapters where, in the first, the toxic
activity was determined, through the median lethal dose test (LD50) in Artemia salina, and the
antimicrobial activity of this species was carried out as part of the test. of sensitivity by the agar
diffusion method, and by determining the minimum inhibitory concentration (MIC). In the
second chapter, the healing activity of ointments containing different concentrations of
methanol extracts from M. dubia fruits in rabbits was evaluated. For this, 12 healthy adult
rabbits were used, which were randomly divided into groups of three rabbits each, treated once
a day topically, with the ointments at the following concentrations: 250 μg/g, 350 μg/g, 500 μg/
ge 1000 μg/g; and a group with an equal number of rabbits was considered a control.

MEMBROS DA BANCA:
Externo ao Programa - 2035814 - IGOR MANSUR MUNIZ
Externo à Instituição - ALEXANDRE ZANDONADI MENEGUELLI - Estácio
Externo à Instituição - FRANCISCO CARLOS DA SILVA - São Lucas
Externo à Instituição - JERONIMO VIEIRA DANTAS FILHO - UNIR