MOLECULAR EPIDEMIOLOGY OF BACTERIAL BIODIVERSITY RESISTANT TO CARBAPENEMIC ANTIMICROBIALS IN CLINICAL SAMPLES IN THE SOUTHWESTERN AMAZON
Bacterial biodiversity; resistant microorganisms; resistance to carbapenems;
molecular epidemiology; GAL
With each new generation of antimicrobials, bacteria evolve and become
increasingly multiresistant, affecting all social classes and all ages. In addition to causing
disease in humans, they are also a cause of concern in animal husbandry, food production,
and the economy. Brazil does not have compiled statistical data on this problem without
revealing how diverse the biodiversity is responsible for it. This study aimed to describe
the molecular epidemiology of bacteria resistant to carbapenems in clinical samples in
the Southwestern Amazon. And as specific objectives to identify bacterial species
resistant to carbapenems and analyze the molecular epidemiological profile of genes
encoding carbapenemases. The methodology of this work consisted of compiling the
results of tests obtained in the Research of Resistance Genes of the Central Laboratory of
Rondônia Public Health - LACEN/RO from 2018 to 2021, through the GAL platform and
the laboratory's internal registry. In addition to bibliographic review through periodicals,
books, and digital channels, among other means. It was concluded that biodiversity goes
beyond what is shown in epidemiological bulletins as the evolution of resistance to these
antimicrobials has increased and been shared between different classes.